February 26, 2024

Rising adoption of molecular cloning techniques to drive the growth of Electrocompetent Cells market

The global Electrocompetent Cells Market is estimated to be valued at US$ 2.07 Bn in 2023 and is expected to exhibit a CAGR of 10.% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.

Market Overview:
Electrocompetent cells are bacteria or yeast cells that have been treated to become competent, meaning capable of taking up foreign DNA or plasmids from their surroundings through electrophoresis. When a brief electric pulse is applied, it creates temporary pores in the cell membrane through which DNA can enter. Electrocompetent cells find widespread application in molecular cloning techniques like DNA transformation, site-directed mutagenesis, and protein expression studies. They help accelerate biomedical research and the development of new therapeutic agents.

Market key trends:
One of the key trends in the electrocompetent cells market is the development of specialized cell lines for enhanced transformation efficiencies. For instance, electrocompetent E. coli strains like DH5╬▒ and TOP10 have routinely yielded transformation efficiencies greater than 1×10^9 colony forming units per microgram of plasmid DNA. Other cell lines like MAX Efficiency┬« DH10B and Stbl3TM are engineered to maintain plasmid stability. Additionally, the emergence of Gibson assembly, an isothermal DNA assembly method, has boosted the demand for electrocompetent cells. Gibson assembly relies on the use of Electrocompetent E. coli cells for recombining multiple DNA fragments simultaneously in a single reaction. It has gained widespread usage in gene synthesis, genome engineering, and synthetic biology applications.
Porter’s Analysis
Threat of new entrants: The threat of new entrants is moderate due to the high costs associated with R&D and manufacturing facilities. Furthermore, established players have strong brand recognition and distribution networks.
Bargaining power of buyers: The bargaining power of buyers is high since electrocompetent cells are available from various manufacturers. However, certain cell types may require expertise in use.
Bargaining power of suppliers: The bargaining power of suppliers is moderate as raw materials used in electrocompetent cells manufacturing such as bacterial strains and medium components are not highly specialized.
Threat of new substitutes: The threat of new substitutes is low as there are limited substitutes that offer the same performance and reliability as electrocompetent cells for DNA transformation.
Competitive rivalry: Competition in the electrocompetent cells market is intense as major players compete on the basis of product quality, portfolio, and pricing.

Key Takeaways
The global Electrocompetent Cells market is expected to witness high growth, exhibiting a CAGR of 10% over the forecast period, due to increasing R&D investments and adoption of gene cloning technology.

Regional analysis
North America dominated the market in 2023, accounting for around 35% of the global market share. This is attributed to presence of leading pharmaceutical and biotech companies conducting R&D activities. Asia Pacific is expected to witness the fastest growth during the forecast period owing to rising biomedical research and increasing government funding in countries such as China and India.

Key players
Key players operating in the electrocompetent cells market are Thermo Fisher Scientific Inc., Merck KGaA, Agilent Technologies, Inc., QIAGEN N.V., New England Biolabs, Inc., GenScript Biotech Corporation, Lucigen Corporation, Takara Bio Inc., Delphi Genetics S.A., IBA GmbH, Scarab Genomics LLC, Zymo Research Corporation, Bioline GmbH (Meridian Bioscience), SelectScience, Biosearch Technology. Thermo Fisher Scientific holds the leading market position due to its broad electrocompetent cells portfolio for various cloning applications